Portal Hypertension and Gross Splenomegaly in Uganda
نویسندگان
چکیده
منابع مشابه
Splenomegaly and left sided portal hypertension
Results: Thirty four out of 53 patients of the study, underwent both endoscopy and US investigations, 9 underwent endoscopy only and 10 underwent only US examination. Fourteen out of 34 patients (i.e. 43%) had endoscopic findings of varices or congestive gastropathy and 15 out of 34 (i.e. 44%) had abnormal circulation around the spleen in the ultrasound examination. Among the 19 patients who un...
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18 Certain pathological changes, including angiogenesis, actively contribute to the 19 pathogenesis of splenomegaly in portal hypertension (PH), although the detailed 20 molecular and cellular mechanisms remain elusive. In this study, we demonstrated 21 that endothelial Grb-2-associated binder 1 (Gab1) plays a negative role in 22 PH-associated splenomegaly independent of angiogenesis. PH, which...
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Bleeding owing to portal hypertensive colopathy, a form of large bowel angiodysplasia, as a cause of increased blood transfusion requirement is described in a 74 year old man with idiopathic myelofibrosis. The proposed mechanism and the potential therapeutic options for this rare complication of myelofibrosis are discussed.
متن کاملEndothelial Gab1 deficiency aggravates splenomegaly in portal hypertension independent of angiogenesis.
Certain pathological changes, including angiogenesis, actively contribute to the pathogenesis of splenomegaly in portal hypertension (PH), although the detailed molecular and cellular mechanisms remain elusive. In this study, we demonstrated that endothelial Grb-2-associated binder 1 (Gab1) plays a negative role in PH-associated splenomegaly independent of angiogenesis. PH, which was induced by...
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A 39-year-old nulliparous female was admitted with massive splenomegaly. Computed tomography of abdomen revealed multiple aneurysms in the distal half of the splenic artery. Splenic artery aneurysms are rare in nulliparous women and most cases are reported in females with a past history of pregnancy. Splenic artery aneurysms, though very rare are clinically significant as they have a high prope...
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ژورنال
عنوان ژورنال: BMJ
سال: 1961
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.5218.15